Therapy during pregnancy involves the use of various drugs including the beta-blocker family, used in the treatment of some cardiomyopathies, cardiac arrhythmias and arterial hypertension. They are not responsible for an increase in the risk of birth defects, so in most cases pharmacological treatment during pregnancy is not only not contraindicated, but is absolutely recommended to maintain good clinical compensation of Cardiomyopathy, of fundamental importance for the regular progress of the pregnancy itself. In any case, management of these pregnancies by a multidisciplinary group that includes specialists in cardiology, obstetrics, obstetric ultrasound and echocardiography, perinatal toxicology, paediatrics is indicated.

Whenever a drug is used for the first time in the treatment of diseases, the patient is faced with two possible effects. The "placebo effect", i.e. a perceived or real benefit on the part of the patient who believes he is undergoing an effective treatment for his clinical condition even if the medicine does not contain active properties. It is the "nocebo" effect (from the Latin "nocere", to damage), that is, the disturbing shadow of side effects. The detailed information leaflets of medicines, the so-called "leaflets", list a long list of possible negative health effects. These fears, fueled by negative expectations, can trigger the phenomenon. The tools to overcome the problem are correct information and the relationship of trust between doctor and patient.